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Your First 90 Days on Medical Weight Loss

The first 90 days on a GLP-1 programme set the foundation for everything that follows. Knowing what's normal — and what to do about it — means you won't get discouraged or make the mistakes that slow progress down.

The first few weeks: what's actually happening

Appetite usually drops within the first week or two — you feel full sooner, cravings quiet down, and food becomes less central. Some nausea early on is common and usually mild: eat slowly, keep meals smaller, and go easy on rich or greasy food while your body adjusts. If nausea is affecting your daily function, message us — there are straightforward ways to manage it, and you don't need to push through.

Build the foundations alongside the medication

The medication reduces appetite — it doesn't do the work for you. It makes the right habits dramatically easier to keep; the habits still need to exist.

  • Protein at every meal. In a calorie deficit, your body will burn muscle if protein is too low. Breakfast, lunch and dinner — every time. Keeping muscle while you lose fat covers this properly.
  • Daily movement. A 20–30 minute walk each day does more than most people realise. Build the habit first; intensity can come later.
  • Sleep. Under six hours actively works against fat loss and drives hunger hormones up.

The scale is not your daily report card

Weight bounces day to day with hydration, sodium and digestion — a Tuesday blip means nothing on its own. Watch the weekly average. A slow, consistent downward trend across weeks is what success looks like, not a dramatic drop every morning. Plateaus happen; a flat fortnight is information, not failure — raise it at your check-in.

What month three tends to look like

Your dose has been stepped up to a level that's working, the early side effects have usually settled, and the habits are starting to carry themselves. This is when the weekly trend becomes convincing — and when your check-in data lets your clinician tune the plan to you.

Message the care team if

  • Nausea or stomach upset is severe, ongoing, or affecting your day.
  • You've missed a dose or want to change your injection day.
  • The trend has been flat for a few weeks and you're not sure why.

Ninety days from now, the medication, the habits and the data will all be pulling in the same direction. One week at a time. You've got this.

Questions about your protocol?

Your care team can review your symptoms, bloods and dose. Start a secure message and we'll get back to you.

Ask your care team